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NCSU College of Veterinary Medicine
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Yevgeny Brudno B.A University of Pennsylvania, Ph.D. Harvard University Postdoc: Harvard University Assistant Professor Department of Biomedical Engineering CMI member LCCC member Address: Joint Department of Biomedical Engineering 911 Oval Drive Mailbox 7115 4208B, Engineering Building III Raleigh, NC 27695 Email : ybrudno@ncsu.edu https:// pharmaco.bme.unc.edu / Title : Laboratory for Molecular Pharmacoengineering Research emphasis: Research in the Brudno lab focuses on exploiting cutting – edge chemical, bio – material and nanomedicine tech – nologies to understand physiological responses during disease and re – generation and fulfill critical unmet needs in the clinic . His group uses chemical prodrug therapy, controlled drug delivery and nanomedicine to enable new forms of cancer chemo – therapy and immunotherapy as well as treatment of infection and other diseases . Application: Sustained Drug Release Refillable Drug Depots Drug D elivery Cancer therapeutics Selected publications: Brudno Y, Desai R, Kwee ChemMedChem . 10(4): 617 – 620 (2015) Brudno Y, Silva EA, Kearney CJ, Lewin S, Aizenberg M, Mooney Proceedings of the National Academy of Science 111(35): 12722 – 7 ( 2014) Brudno Y, Ennett AB, Chen R, Aizenberg M, Mooney DJ. through temporal control over multiple pro – angiogenic and pro – Biomaterials 34(36): 9201 – 9209 (2013 ) Brudno Y, Birnbaum ME, Kleiner Translation, Selection, and Amplification System for Peptide Nature Chemical Biology 6: 148 – 155 (2009). Collaboration potential: Controlled Local Release of Therapeutic Molecules Drug modification and Prodrugs Biomaterial systems Nanoparticles + Nanotechnology
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