SHAM = slope, height, area, first time moment.
These pharmacokinetic (PK) parameters are useful for non-compartmental and identifying the basic model, the type of model it is and the structure of the model that can describe the data. This model can then be used for simulations for calculating what may be expected in untested scenarios.
For example the basic model/type/structure should be analyzed in terms of its linearity and stationarity:
Could be a:
Mammillary Plasma Clearance Model
Organ Clearance Model
Reversible Compartment Model