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1Keyboarding EssentialsLesson 1 Learn the Home Keys Lesson 2 Review the Home Keys Lesson 3 Learn E and H Lesson 4 Learn R and I Lesson 5 Review E, H, R, and I Lesson 6 Learn T and O Lesson 7 Learn G and N Lesson 8 Learn Left Shift and Period Lesson 9 Review Left Shift T, O, G, N, and Period Lesson 10 Learn C and U Lesson 11 Learn W and Right Shift Lesson 12 Learn X and M Lesson 13 Review C, U, W, X, M, and Right Shift Lesson 14 Learn B and Y Lesson 15 Learn V and P Lesson 16 Learn Q and Comma Lesson 17 Review B, Y, V, P, Q, and Comma Lesson 18 Learn Z and Colon Lesson 19 Learn Apostrophe and Quotation Marks Lesson 20 Learn Hyphen and Diagonal Lesson 21 Review Z, Colon, Apostrophe, Quotation Marks, Hyphen, and Diagonal Lesson 22 Learn Caps Lock and Question Mark Lesson 23 Learn Tab Lesson 24 Review Caps Lock, Question Mark, and Tab Lesson 25 Learn the Ten Key

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The number of pages within the document is: 44

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2019-02-05 19:28:22.345567

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Aims and learning outcomesPharmacokinetics is a fundamental scientiÞc discipline that underpinsapplied therapeutics. Patients need to be prescribed appropriate medicines for a clinical condition. The medicine is chosen on the basis of an evidence- based approach to clinical practice and assured to be compatible with any other medicines or alternative therapies the patient may be taking.The design of a dosage regimen is dependent on a basic under-standing of the drug use process (DUP). When faced with a patient who shows speciÞc clinical signs and symptoms, pharmacists must always ask a fundamental question: ÔIs this patient suffering from a drug-related problem?Õ Once this issue is evaluated and a clinical diagnosis is avail- able, the pharmacist can apply the DUP to ensure that the patient is prescribed an appropriate medication regimen, that the patient under- stands the therapy prescribed, and that an agreed concordance plan is achieved.Pharmacists using the DUP consider:Need for a drugChoice of a drugGoals of therapyDesign of regimen ÐRoute ÐDose and frequency ÐDuration Monitoring and reviewCounsellingOnce a particular medicine is chosen, the principles of clinical pharmaco-kinetics are required to ensure the appropriate formulation of drug is chosen for an appropriate route of administration. On the basis of the patientÕs drug handling parameters, which require an understandingof 1Basic pharmacokinetics Soraya Dhillon and Kiren Gill

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The number of pages within the document is: 341

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John Fowles

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2019-02-08 23:38:58.303250

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The number of pages within the document is: 303

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raatroc

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2019-02-05 23:07:59.660154

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Volume 2B Notice to Applicants Medicinal products for human use Presentation and format of the dossier Common Technical Document (CTD) Introduction Edition June 2006 Module 1 Edition May 2008 Module 2 Edition July 2003 Module 3 Edition July 2004 Module 4 Edition July 2004 Module 5 Edition July 2004 Herbals Edition July 2003

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Department of Veterans Affairs

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2019-02-08 22:26:20.832425

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Page 1 Updated 7/08/13 PORTLAND VETERANS AF FAIRS MEDICAL CENTER INSTITUTIONAL ANIMAL CARE AND USE COMMITT EE (PVAMC IACUC ) ANIMAL CARE AND USE GUIDELINES GUIDELINES FOR ANIMAL CARE WHILE EMPLOYING THE EXPERIMENTAL AUTOIMMUNE ENCEPHALITIS (EAE) MODEL IN RODENTS Guidelines. 1. At the time of inoculation with the substance eliciting an EAE effec t, a baseline body weight of the animal will be obtained and recorded in the laboratory notebook. A red – tag of the person responsible for the care of the animals will be p laced on each applicable animal cage. The red tag is supplementary to the originally issued cage card which details, among other information, the protocol number, Principal Investigator, and laboratory telephone number. Red tags may be obtained from the Veterinary Medical Unit. 2. Animals will be monitored by the PI or an individual designated by the PI a minimum of once daily, beginning in advance of the point in time when experimental effects such as paresis or paralysis are expected. Minimum once dai ly monitoring will continue until the conclusion of the acute phase of the experiment. In the relapsing models, if animals are to survive after the resolution of the acute phase, monitoring shall be done once daily by the PI or an individual designated by the PI until the termination of the experiment. Monitoring will include the graded score of the EAE involvement, hydration status, general condition and activity level of the animal. Monitoring observations will be recorded in ink in a bound laboratory notebook. The date, time of observation, and the name of the individual observing the animals will be recorded with each set of observations. 3. At the time at which the earliest experimental effects are expected and until the conclusion of the acute pha se of the experiment, an additional water source consisting of gelatin cubes or a suitable substitute will be placed on the cage floor ad lib , moistened rodent blox will be provided on the cage floor ad lib , and body weight will be measured daily. At 30% weight loss from baseline, regardless of graded score of EAE involvement or clinical condition, animals will be given intraperitoneal supplemental fluid therapy consisting of lactated Ringers or normal saline (10% volume/bodyweight/24hours) until body weig ht returns to within 10% of baseline. Body weights and documentation of fluid administration will be made in the laboratory notebook. If animals do not respond to fluid treatment, they will be humanely euthanized. 4. Guidelines for animal monitoring mus t be signed, on file with the IACUC and strictly followed. Prior arrangement may be made to contract the Veterinary Services to perform observations, husbandry, and fluid therapy. Animals undergoing the EAE model CHECK ONE: I agree to comply with the following guidelines. I have attached written justification for deviation from these guidelines. Principal Investigator Date

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The number of pages within the document is: 17

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Murata Manufacturing Co., Ltd.

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2019-02-09 17:57:57.732140

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Ofcom

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2019-02-09 19:00:25.125135

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M i g h t y Radio community r a d i o licence application form 1. Station Name Guidance Notes What is the proposed station name? T his is the name you expect to use to identify the station on air. Mighty Radio 2. Community to be served Guidance Notes Define the community or communities you are proposing to serve. Drawing from various sources of data (e.g. from the Office of Population, Census and Survey) and in relation to your proposed coverage area, please determine the size of the population concerned and the make – up of the population as a whole, along with any relevant socio – economic information that would support your application. (Please tell us the sources of the information you provide.) Answer in fewer than 300 words: It is a legislative requirement that a service is intended primarily to serve o ne or more communities (whether or not it also serves other members of the public) and we need to understand who comprises that community or communities. The target community will also be specified in the licence, if this application is successful. The le or work or undergo education or training in a particular area or locality, or people who have one or more interests or characteristics in common. In 2010 Southport constituency’s estimated population wa s 90,197. Gender breakdown: Females make up 52.5% of residents. 60% of Residents are of working age. 16.5% are children with a higher than average proportion of over 65 year olds at 22.6%. Just 1.8% are non – white British. House prices are 42% higher than t he average Sefton area price with those living in RSL properties less than half for the Sefton area as a whole. Benefit claimants for the area equate to half the Sefton area average. However, compared to the rest of the Sefton area, wages are considerably lower in Southport. (From Southport Parliamentary Constituency Profile 2012) 66.1% of workers travel by car. (Southport Area Committee Profile) Southport is Conservative . Southport is a coastal seaside resort and a linear settlement and can only be approached in a limited number of directions by road. It has a long history of leisure and recreation and is dependent upon tourism. The town hosts annual events (including a major flower show, air – show, and the British Fireworks Championships. The town is 4th in the country for notable investment. (N.Y. Times) The town is often referred to as ‘England’s Golfing Capital and has the highest concentration of championship links courses. Southport has many attractions and with its wide boulevard is home to a plethora of cafes, bars and restaurants, hotels, and clubs resulting in a vibrant night life and influx of younger people in the evenings. It is a major shopping centre with a wide range of businesses. In short , a vibrant seaside town with a large transien t population and a residential population with a higher than average element of over 65 year olds. The largest non – British community is Polish with an estimate d 3000 in 2009 (Southport Visite r), which makes up 3.3 % of the area population. 3. Propos ed area Guidance Notes What is the area you propose to serve? Although we believe it is helpful to set guidance that frequency availability may often limit transmission powers to around 25 watts and the coverage radius to around 5km, we are adopting a mor e flexible approach and will consider applications for wider areas where applicants can demonstrate that the proposed coverage area will better serve the target community, and where it is technically possible. www.ofcom.org.uk/__data/assets/pdf_file/0020/10 1459/community – radio – future – licensing – technical – policy – statement.pdf

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The number of pages within the document is: 268

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Sudeep

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2019-02-08 23:10:06.639917

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2019-02-08 22:27:16.776784

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